Test profile
Serum Protein Electrophoresis (SPE)
Key Aspects of the SPEP Test Purpose: Identifies abnormal, excessive, or deficient proteins often indicating cancer, autoimmune disorders, or kidney/liver issues. Method: A blood sample is applied to a gel or capillary…
- Tests included
- 8
- Sample
- Serum
- Preparation
- No fasting needed
- Collection
- At your home
Tests included (8)
AlbuminDetails
Key Aspects of Albumin:
- Primary Functions: Maintains fluid balance by preventing water from leaking out of blood vessels (oncotic pressure) and acts as a transport mechanism for molecules like calcium, progesterone, and bilirubin.
- Production & Life Span: Synthesized in the liver at a rate of 10–15 grams per day, with a serum half-life of approximately 21 days.
- Albumin Testing: A simple blood test, often part of routine metabolic panels, measures levels to assess liver/kidney health or nutritional status.
- Low Albumin Symptoms (Hypoalbuminemia): Frequently causes edema (swelling) in the feet, ankles, or abdomen, along with fatigue, weakness, and loss of appetite.
- High Albumin (Hyperalbuminemia): Usually caused by acute dehydration.
- Clinical Use: Human albumin is also manufactured for intravenous use in treating severe injuries, burns, and surgeries to stabilize blood volume.
Total Protein, SerumDetails
Key Aspects of the Test
- What it Measures:
- Albumin: Produced by the liver, it prevents fluid leakage from blood vessels and transports substances.
- Globulins: Produced by the immune system and liver, they fight infections.
- A/G Ratio: The ratio of albumin to globulins is often included.
- When it is Used: To investigate unexplained weight loss, fatigue, or symptoms of kidney/liver disease (e.g., swelling, jaundice).
- Procedure: A blood sample is drawn from a vein. Generally, no fasting is required, but it can depend on whether other tests are ordered simultaneously.
Interpreting Results
- Low Protein Levels: Can indicate liver disease (e.g., cirrhosis), kidney disease (kidney damage allows protein to leak into urine), or malnutrition/malabsorption.
- High Protein Levels: Can be caused by chronic infections (e.g., HIV, Hepatitis C), inflammatory conditions, or bone marrow disorders like multiple myeloma.
- A/G Ratio: Low ratios suggest autoimmune diseases or chronic inflammation, while high ratios may indicate leukemia or genetic deficiencies.
- What it Measures:
Alpha-1 GlobulinsDetails
Alpha-1 Globulins - Lab test
Alpha-2 GlobulinsDetails
Alpha-2 Globulins - Lab test
Beta-1 GlobulinsDetails
Beta-1 Globulins - Lab test
Beta-2 GlobulinsDetails
Beta-2 Globulins - Lab test
Gamma - GlobulinsDetails
Gamma - Globulins - Lab test
A/G RatioDetails
A/G Ratio - Lab test
About this test profile
Key Aspects of the SPEP Test
- Purpose: Identifies abnormal, excessive, or deficient proteins often indicating cancer, autoimmune disorders, or kidney/liver issues.
- Method: A blood sample is applied to a gel or capillary, and an electric current separates proteins into five main fractions: Albumin, Alpha-1, Alpha-2, Beta, and Gamma globulins.
- What it Detects:
- M-spike: A sharp peak in the gamma region, indicating a monoclonal gammopathy (e.g., Multiple Myeloma, MGUS, or Waldestroms macroglobulinemia).
- Low Albumin: Suggests liver disease, malnutrition, or kidney dysfunction.
- Polyclonal Increase: Often due to chronic inflammation, infections, or autoimmune disease.
- Associated Tests: Often followed by Immunofixation Electrophoresis (IFE) to specifically identify the type of abnormal immunoglobulin.
- Symptoms Warranting Test: Unexplained bone pain, fatigue, weight loss, anemia, or high calcium levels.
Preparation and Results
- Preparation: Usually no fasting is required, though your doctor might advise it.
- Risks: Very safe; minimal risk of bruising or pain at the site of blood collection.
- Results: Results are typically available within a few days.
Potential Findings
- Monoclonal Gammopathy: A monoclonal spike in the gamma or beta region.
- Inflammation: Increased alpha-1 and alpha-2 globulins.
- Liver Disease: Often decreased albumin and increased gamma globulins.
- Nephrotic Syndrome: Low albumin, high alpha-2, or low gamma globulins.
Preparation
- No fasting is needed for this test. You can book any available slot.
- Keep your doctor’s prescription or test request handy if you have one, and take regular medicines as your doctor has advised.
- Tell the sample collector if you take blood thinners, and wear a sleeve that rolls above the elbow.
How home sample collection works
- 1
Choose your tests
Add single tests or a package to the cart and check fasting needs.
- 2
Pick a collection slot
Half-hour slots from 30 minutes ahead, up to 10 days out. Pay online.
- 3
A sample collector visits
They confirm the visit with a one-time code, then take the sample.
- 4
Report in your account
The lab uploads the report and you are notified to download it.
Where we collect samples at home
Lab tests with home sample collection reach 70 Hyderabad pin codes today, across these areas:
- Kachiguda
- LB Nagar
- Ameerpet
- ECIL
- Jubilee Hills
- Neredmet
- Saidabad
- Sanathnagar
- Tolichowki
- Yousufguda
- Amberpet
- Khairatabad
- Kukatpally
- Manikonda
- Nizampet
- Secunderabad
- Tarnaka
- Uppal
- Vanasthalipuram
- Jeedimetla
- Mehdipatnam
- Musheerabad
- Nacharam
- Suchitra
- Trimulgherry
Coverage differs street to street and grows as professionals join. Check your pin code to see what reaches your address.
Frequently asked questions
How much does Serum Protein Electrophoresis (SPE) cost in Hyderabad?
Serum Protein Electrophoresis (SPE) costs ₹899 on Aish Health in Hyderabad, down from ₹1,299. There is no separate home collection fee; any GST or busy-hour charge is shown before you pay.
Do I need to fast before Serum Protein Electrophoresis (SPE)?
No, fasting is not needed for this test, so you can book any available slot.
What sample is collected for Serum Protein Electrophoresis (SPE)?
Serum sample is collected at your home by a sample collector.
How many tests are in Serum Protein Electrophoresis (SPE)?
Serum Protein Electrophoresis (SPE) includes 8 tests, all listed on this page. Compare them with what your doctor has asked for before booking.
Can I cancel a lab test booking?
Yes. Cancel before a sample collector accepts or more than 1 hour before the slot for a full refund. Within 1 hour of the slot there is no refund, and once the sample collector is on the way the booking can no longer be cancelled.
Can I book tests for a family member?
Yes. Add them as a family member in your account and choose them as the patient when booking, so the report is filed under their name.
Can I pay cash when the sample is collected?
No. Lab tests booked on the website or app are paid online when you book, by card, UPI or your Aish Health wallet.
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